Dr. Marta Grazzini is an English-speaking Dermatologist and Venereologist. She graduated from
the Medical School of the University of Pisa in 2007. Dr. Grazzini earned the
specialization in Dermatology and Venereology from the University of Florence
in 2012. She is currently pursuing a doctorate (Ph.D.) at the
University of Florence.
Dr. Grazzini’s main area of research is the dermatological oncology
and early detection of melanoma with the use of the modern non-invasive
diagnostic methods such as dermoscopy and videodermoscopy. Dr. Grazzini lived
extensively in the US and conducted research at leading American scientific
institutions such as the Memorial Sloan Kettering Cancer Center in New York
City and Harvard Medical School in Boston.
SYPHILISSyphilis is a sexually transmitted disease caused by the spirochete bacteria Treponema pallidum. Syphilis is treatable with antibiotics, but can have serious complications if not treated soon after infection. Both men and women can have syphilis, and it can be passed on from an infected pregnant woman to her unborn infant.
Syphilis occurs in 3 stages. In stages 1 and 2 a person is infectious during sexual contact. The condition is transmitted by skin-to-skin contact with an infected area. Sores develop on the site that has touched the infectious area. Depending on the type of sexual contact, sores may therefore appear on or near the genitals, lips, fingers or anus. The hard, usually painless sores can appear any time between 10 days to 3 months after acquiring the infection. Two to four months after infection there may be symptoms including a skin rash, patchy hair loss, fever, lumps around the genitals and anus, or general tiredness. If not treated, these symptoms may disappear and then recur over the next two years. The rash can be all over the body and is very contagious. An infected, but untreated, person may remain infectious through sexual contact for 2 years. HAIR LOOSMany cases of hair loss are temporary (for example, due to chemotherapy) or a natural part of ageing and don't need treatment. However, hair loss can have an emotional impact, so it is best to seek treatment if you are uncomfortable with your appearance. If hair loss is caused by an infection or another dermatological condition, such as lichen planus or discoid lupus, treating the underlying problem may help to prevent further hair loss. Male-pattern baldness is can also be treated with topical or systemic treatment. |
The usual therapies for individual AK work destructively by surgically removing the lesion . These should always be considered for isolated lesions or early presentations of AKs. Destructive therapies include liquid nitrogen cryotherapy, curettage with or without electrodessication, and shave excision. The benefits of these techniques are that they are quick, procedurally simple, and easy. Cryotherapy is one of the most commonly utilized techniques, with liquid nitrogen being the most frequently selected cryogen. Applying cryotherapy to the affected area lowers the skin to temperatures that destroy atypical AK cells. This technique is ideal if lesions are scattered or limited in number, or for patients who are non-compliant with topical regimes . Cryotherapy is advantageous in that it is generally well tolerated and does not require local anesthetic, but downsides include pain during the procedure and frequent permanent hypopigmentation. Curettage consists of using a curette to mechanically remove atypical cells. A shave excision using a surgical blade is another technique. These may be followed by electrocautery, which will destroy additional atypical cell layers as well as provide hemostasis. These techniques are most appropriate for treating individual AKs, cases where a biopsy is required to rule out SCC, or for hypertrophic AKs that are refractory to other treatments. For patients with multiple AKs a different therapeutic approach, known as field therapy, is needed with the goal of “field therapy” for the eradication of both the clinically visible and subclinical AKs within the treatment area . As regards as chemical treatments, Diclofenac and Imiquimod are the most frequent used in Europe.
Doctor Marta Grazzini is specialized in diagnosis and treatment of melanoma and non melanoma skin cancer. Doctor Grazzini treat skin cancer with a variety of surgical and non-surgical techniques.
SKIN CANCER PREVENTION
The skin check by the dermatologist is the most
effective method for the skin cancer prevention. The frequency of the
dermatlogical skin check is variable and mainly depends on patient personal and family history of melanoma and patient skin type
(subjects with very light skin have higher risk of skin cancer). The frequency of the dermatological control should also
depend on the amount and the type of sun
exposure that the patient has had during his/her childhood. Sun burns is the most important risk factor
for cutaneous cancer. Based on patient personal characteristics, the
dermatologist will recommend a specific frequency for follow-up visits. On
average, a dermatologic skin check is recommended every 12 months
Melanoma and Non Melanoma Skin Cancer
Melanoma is the
most serious type of skin cancer. It begins in skin cells called melanocytes.
Though melanoma is predominantly found on the skin, it can even occur in the
eye.
The first sign
of melanoma is often a change in the size, shape, or color of a mole. But
melanoma can also appear on the body as a new mole. The chance of getting
melanoma increases as you get older, but people of any age can get melanoma. In
fact, melanoma is one of the most common cancers in young adults. Melanoma is a
serious and sometimes life-threatening cancer. If melanoma is found and treated
in its early stages, the chances of recovery are very good. If it is not found
early, melanoma can grow deeper into the skin and spread to other parts of the
body.
The most common non-melanoma
skin cancers are basal cell carcinoma and squamous cell carcinoma. They
two type of cancer are very common in Caucasian population. They usually start
in the basal cells or squamous cells, which is how they get their names. Most
non-melanoma skin cancers develop on sun-exposed areas of the body, like the
face, ear, neck, lips, and the backs of the hands. Depending on the type, they
can be fast or slow growing, but they rarely spread to other parts of the body.
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OFFICE LOCATIONS AND CONTACTS
Office in Florence Borgo San Jacopo 64 E-mail: marta.grazzini@unifi.it Tel: 055-2741503
Office in Lucca Borgo Giannotti 405 Tel: 0583-341804
Office in Capannori (Lucca) Via Rossi, n 1 Tel. 347-4947868
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